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Article

Natural LILRB1 D1-D2 variants show frequency differences in populations and bind to HLA class I with various avidities.

Immunogenetics - 1 Dec 2022

Liu Fuguo, Cocker Alexander T H, Pugh Jason L, Djaoud Zakia, Parham Peter, Guethlein Lisbeth A

Abstract excerpt

Leukocyte immunoglobulin-like receptor B1 (LILRB1) is widely expressed on various immune cells and the engagement of LILRB1 to HLA class I and pathogen-derived proteins can modulate the immune response. In the current study, 108 LILRB1 alleles were identified by screening the LILRB1 locus from the 1000 Genomes Phase 3 database. Forty-six alleles that occurred in three or more individuals encode 28 LILRB1...

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Identifiers

PMID: 35562487
DOI: 10.1007/s00251-022-01264-7
PMCID: PMC9103611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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