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Article

Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.

Immunogenetics - 1 Jan 2014

Bashirova Arman A, Apps Richard, Vince Nicolas, Mochalova Yelizaveta, Yu Xu G, Carrington Mary

Abstract excerpt

Leukocyte immunoglobulin-like receptor (LILR)B3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ, which bears a cytoplasmic tail with an...

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Source

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Identifiers

PMID: 24096970
DOI: 10.1007/s00251-013-0730-9
PMCID: PMC3877738

Genes

LILRA6
LILRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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