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Article

Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations.

Journal of human genetics - 1 Nov 2015

Hirayasu Kouyuki, Arase Hisashi

Abstract excerpt

Human leukocyte immunoglobulin-like receptors (LILR) are a family of 11 functional genes encoding five activating (LILRA1, 2, 4-6), five inhibitory (LILRB1-5) and one soluble (LILRA3) form. The number of LILR genes is conserved among individuals, except for LILRA3 and LILRA6, which exhibit copy-number variations. The LILR genes are rapidly evolving and showing large interspecies differences, making it difficult...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26040207
DOI: 10.1038/jhg.2015.64

Genes

LILRA3
LILRA1
LILRA6
LILRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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