Article
LILRB1 polymorphism and surface phenotypes of natural killer cells.
Human immunology - 1 Oct 2010
Davidson Chelsea L, Li Nicholas L, Burshtyn Deborah N
Abstract excerpt
Leukocyte Ig-like receptor (LIR)-1 is an inhibitory receptor that binds a broad range of class I HLA molecules and is encoded by the LILRB1 gene within the leukocyte receptor complex. In contrast to uniform expression on monocytes and B cells, LIR-1 expression on natural killer (NK) cells varies considerably between individuals. To investigate how polymorphism is related to the observed patterns of expression, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
