Article
Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.
Human immunology - 1 Jun 2010
Antoun Ayman, Jobson Shirley, Cook Mark, O'Callaghan Chris A, Moss Paul, Briggs David C
Abstract excerpt
NKG2D is an important activating receptor on NK cells and T-cells and has a diverse panel of ligands (NKG2DL) which include the ULBP and RAET1 proteins. Several NKG2DL exhibit a considerable degree of genetic polymorphism, and although the functional significance of such allelic variation remains...
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