Article
Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.
Journal of human genetics - 1 Jul 2021
Hirayasu Kouyuki, Sun Jinwen, Hasegawa Gen, Hashikawa Yuko, Hosomichi Kazuyoshi, Tajima Atsushi, Tokunaga Katsushi, Ohashi Jun, Hanayama Rikinari
Abstract excerpt
Leukocyte immunoglobulin (Ig)-like receptors (LILRs) are encoded by members of a human multigene family, comprising 11 protein-coding genes and two pseudogenes. Among the LILRs, LILRB3 and LILRA6 show the highest homology with each other, along with high allelic and copy number variations. Therefore, it has been difficult to discriminate between them, both genetically and functionally, precluding disease...
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