Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Suicide-Related Single Nucleotide Polymorphisms, rs4918918 and rs10903034: Association with Dementia in Older Adults.

Genes - 21 Nov 2022

Abramova Olga, Soloveva Kristina, Zorkina Yana, Gryadunov Dmitry, Ikonnikova Anna, Fedoseeva Elena, Emelyanova Marina, Ochneva Aleksandra, Andriushchenko Nika, Pavlov Konstantin, Pavlova Olga, Ushakova Valeriya, Syunyakov Timur, Andryushchenko Alisa, Karpenko Olga, Savilov Victor, Kurmishev Marat, Andreuyk Denis, Gurina Olga, Chekhonin Vladimir, Kostyuk Georgy, Morozova Anna

Abstract excerpt

Dementia has enormous implications for patients and the health care system. Genetic markers are promising for detecting the risk of cognitive impairment. We hypothesized that genetic variants associated with suicide risk might significantly increase the risk of cognitive decline because suicide in older adults is often a consequence of cognitive impairment. We investigated several single-nucleotide polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognitive Dysfunction

Share to Dementia

Share to Polymorphism, Single Nucleotide

Share to Suicide

Source

Open in PubMed Open full text

Identifiers

PMID: 36421848
DOI: 10.3390/genes13112174
PMCID: PMC9690628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Suicide-Related Single Nucleotide Polymorphisms, rs4918918 and rs10903034: Association with Dementia in Older Adults.PMID 36421848Read ↗

Intergenic Interactions of ESR1, GSTO1 and AGER and Risk of Dementia in Community-Dwelling Elderly (SADEM Study).Semantic proximity Read ↗

Association of SORL1 polymorphisms and SORL1-APOE ε4 interaction with risk of subjective cognitive decline and mild cognitive impairment in the Chinese population.Semantic proximity Read ↗

Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia.Semantic proximity Read ↗

Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.Semantic proximity Read ↗

The ACE Gene Is Associated with Late-Life Major Depression and Age at Dementia Onset in a Population-Based Cohort.Semantic proximity Read ↗

Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia.Semantic proximity Read ↗

Association of polymorphisms in the LRP1 and A2M genes with Alzheimer's disease in the northern Chinese Han population.Semantic proximity Read ↗

SORL1 Gene is Associated with the Conversion from Mild Cognitive Impairment to Alzheimer's Disease.Semantic proximity Read ↗

rs2070424 of the SOD1 gene is associated with risk of Alzheimer's disease.Semantic proximity Read ↗

Selected LDLR and APOE Polymorphisms Affect Cognitive and Functional Response to Lipophilic Statins in Alzheimer's Disease.Semantic proximity Read ↗

Rare protein-coding variants implicate genes involved in risk of suicide death.Semantic proximity Read ↗

Genetic polymorphisms of lipid metabolism gene SAR1 homolog B and the risk of Alzheimer's disease and vascular dementia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.