Article
Rare protein-coding variants implicate genes involved in risk of suicide death.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2021
DiBlasi Emily, Shabalin Andrey A, Monson Eric T, Keeshin Brooks R, Bakian Amanda V, Kirby Anne V, Ferris Elliott, Chen Danli, William Nancy, Gaj Eoin, Klein Michael, Jerominski Leslie, Callor W Brandon, Christensen Erik, Smith Ken R, Fraser Alison, Yu Zhe, Gray Douglas, Camp Nicola J, Stahl Eli A, Li Qingqin S, Docherty Anna R, Coon Hilary
Abstract excerpt
Identification of genetic factors leading to increased risk of suicide death is critical to combat rising suicide rates, however, only a fraction of the genetic variation influencing risk has been accounted for. To address this limitation, we conducted the first comprehensive analysis of rare genetic variation in suicide death leveraging the largest suicide death biobank, the Utah Suicide Genetic Risk Study...
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