Article
Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.
Journal of neuropathology and experimental neurology - 1 Jan 2015
Nelson Peter T, Wang Wang-Xia, Partch Amanda B, Monsell Sarah E, Valladares Otto, Ellingson Sally R, Wilfred Bernard R, Naj Adam C, Wang Li-San, Kukull Walter A, Fardo David W
Abstract excerpt
Hippocampal sclerosis of aging (HS-Aging) is a common high-morbidity neurodegenerative condition in elderly persons. To understand the risk factors for HS-Aging, we analyzed data from the Alzheimer's Disease Genetics Consortium and correlated the data with clinical and pathologic information from the National Alzheimer's Coordinating Center database. Overall, 268 research volunteers with HS-Aging and 2,957...
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