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Article

Association of polymorphisms in the LRP1 and A2M genes with Alzheimer's disease in the northern Chinese Han population.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Feb 2013

Yuan Quan, Wang Fen, Xue Sufang, Jia Jianping

Abstract excerpt

Low-density lipoprotein receptor-related protein1 (LRP1) and alpha-2-macroglobulin (A2M) are candidate genes for sporadic Alzheimer's disease (SAD). It is not clear whether the LRP1 exon 3 and A2M exon 24 polymorphisms are associated with SAD. In the present study, we used direct sequencing to genotype the LRP1 C766T (rs1799986) polymorphism in exon 3 and the A2M I1000V (rs669) polymorphism in exon 24 in 364...

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Source

Identifiers

PMID: 23186781
DOI: 10.1016/j.jocn.2012.01.052

Genes

LRP1
APOE

Variants

rs1799986
rs1799986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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