Article
Genetic polymorphisms of lipid metabolism gene SAR1 homolog B and the risk of Alzheimer's disease and vascular dementia.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jan 2016
Chen Jen-Hau, Hsieh Ching-Jow, Huang Yi-Ling, Chen Yen-Ching, Chen Ta-Fu, Sun Yu, Wen Li-Li, Yip Ping-Keung, Chu Yi-Min
Abstract excerpt
BACKGROUND/PURPOSE: Lipid metabolism is involved in beta amyloid generation, which has been related with the progression of Alzheimer's disease (AD). No study has explored the association between polymorphisms of SAR1 homolog B (SAR1B) and the risk of dementia previously. METHODS: This is a case-control study. A total of 279 AD and 117 vascular dementia (VaD) patients were recruited from neurology clinics at...
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