Article
Polygenic scores for low lung function and the future risk of adverse health outcomes.
Cardiovascular diabetology - 3 Nov 2022
Zaigham Suneela, Gonçalves Isabel, Center Regeneron Genetics, Engström Gunnar, Sun Jiangming
Abstract excerpt
AIMS: Reduced lung function and adverse health outcomes are often observed. This study characterizes genetic susceptibility for reduced lung function and risk of developing a range of adverse health outcomes. METHODS: We studied 27,438 middle-aged adults from the Malmö Diet and Cancer study (MDCS), followed up to 28.8 years. Trait-specific Polygenic scores (PGS) for forced expiratory volume in 1 s (FEV1) and...
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