Genetic correlation and causal relationships between cardio-metabolic traits and Lung function Impairment

Abstract excerpt

<h4>Background</h4> Associations of low lung function with features of poor cardio-metabolic health have been reported. It is, however, unclear whether these co-morbidities reflect causal associations, shared genetic heritability or are confounded by environmental factors. <h4>Methods</h4> We performed three analyses: 1) cardio-metabolic health to lung function association tests in NFBC1966, 2) cross trait LD scor...

Topics

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• Cardiometabolic Risk Factors
• Disease Susceptibility
• Finland
• Inflammation Mediators
• Lung Diseases
• Metabolic Syndrome
• Public Health Surveillance
• Respiratory Function Tests

Identifiers and source

Literature Corpus work

78962257-1a2d-5e4e-ad5c-2bcd412087fb

DOI

10.1101/2020.09.16.20190306