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Article

Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment.

Genome medicine - 21 Jun 2021

Wielscher Matthias, Amaral Andre F S, van der Plaat Diana, Wain Louise V, Sebert Sylvain, Mosen-Ansorena David, Auvinen Juha, Herzig Karl-Heinz, Dehghan Abbas, Jarvis Debbie L, Jarvelin Marjo-Riitta

Abstract excerpt

BACKGROUND: Associations of low lung function with features of poor cardio-metabolic health have been reported. It is, however, unclear whether these co-morbidities reflect causal associations, shared genetic heritability or are confounded by environmental factors. METHODS: We performed three analyses: (1) cardio-metabolic health to lung function association tests in Northern Finland Birth cohort 1966, (2)...

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Identifiers

PMID: 34154662
DOI: 10.1186/s13073-021-00914-x
PMCID: PMC8215837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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