Article

Genetic risk score-informed re-evaluation of spirometry quality control to maximise power in epidemiological studies of lung function

2024-08-02

Abstract excerpt

<h4>Background and aim</h4> Epidemiological studies of lung function may discard one-third to one-half of participants due to spirometry measures deemed “low quality” using criteria adapted from clinical practice. We aimed to define new spirometry quality control (QC) criteria that optimise the signal-to-noise ratio in epidemiological studies of lung function. <h4>Material and methods</h4> We proposed a genetic ri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b13023fd-4a29-5b1d-a441-8cfbbc7e700f
DOI: 10.1101/2024.07.31.24311269

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic risk score-informed re-evaluation of spirometry quality control to maximise power in epidemiological studies of lung functionDOI 10.1101/2024.07.31.24311269Read

Genetic risk score informed re-evaluation of phenotype quality control to maximise power in epidemiological studies: application to lung function.Semantic proximity Read

Genetic insights into lung function inform better management of respiratory diseases.Semantic proximity Read

Multi-ancestry genome-wide association study reveals novel genetic signals for lung function declineSemantic proximity Read

Framingham Heart Study genome-wide association: results for pulmonary function measures.Semantic proximity Read

Heritability and genome-wide association study of diffusing capacity of the lungSemantic proximity Read

Smoking Interaction with a Polygenic Risk Score for Reduced Lung FunctionSemantic proximity Read

Exploring the genetics of airflow limitation in lung function across the lifespan – a polygenic risk score studySemantic proximity Read

Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGeneSemantic proximity Read

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.Semantic proximity Read

Genome-wide analysis of longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosisSemantic proximity Read

Genome-wide association study of extrapulmonary traits in the context of COPDSemantic proximity Read

Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.Semantic proximity Read