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Article

Associations of genetic risk and smoking with incident COPD

25 Jun 2021

Abstract excerpt

Background Genetic factors and smoking contribute to chronic obstructive pulmonary disease (COPD), but whether a combined polygenic risk score (PRS) is associated with incident COPD and whether it has a synergistic effect on smoking remains unclear. We aimed to investigate the association of the PRS with COPD and explore whether smoking behaviours could modify such association. Methods Multivariable Cox...

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Identifiers

PMID: 34172472
DOI: 10.1183/13993003.01320-2021

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