Article
A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity.
The European respiratory journal - 1 Oct 2021
Zhu Zhaozhong, Li Jiachen, Si Jiahui, Ma Baoshan, Shi Huwenbo, Lv Jun, Cao Weihua, Guo Yu, Millwood Iona Y, Walters Robin G, Lin Kuang, Yang Ling, Chen Yiping, Du Huaidong, Yu Bo, Hasegawa Kohei, Camargo Carlos A, Moffatt Miriam F, Cookson William O C, Chen Junshi, Chen Zhengming, Li Liming, Yu Canqing, Liang Liming
Abstract excerpt
BACKGROUND: Lung function is a heritable complex phenotype with obesity being one of its important risk factors. However, knowledge of their shared genetic basis is limited. Most genome-wide association studies (GWASs) for lung function have been based on European populations, limiting the generalisability across populations. Large-scale lung function GWASs in other populations are lacking. METHODS: We included...
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