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Article

Comparison of Nonsequencing Techniques for Identification of NPM1 Mutations and Associated Blast Morphology in Patients With Acute Myeloid Leukemia.

Archives of pathology & laboratory medicine - 1 Jun 2023

Menegotto Pâmela Rossi, Farias Mariela Granero, Spagnol Fabiane, Siebert Marina, Filippi-Chiela Eduardo Cremonese, Alegretti Ana Paula, Pilger Diogo André

Abstract excerpt

CONTEXT.—: Nucleophosmin 1 (NPM1) mutations affect 20% to 30% of all acute myeloid leukemia (AML) patients; several methods are employed to analyze NPM1 mutations, each of them with its advantages and limitations. OBJECTIVE.—: To compare 3 nonsequencing protocols capable of detecting the main NPM1 mutations and to evaluate nuclear morphometric analysis (NMA) as an alternative to cuplike blast detection. DESIGN.—:...

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Identifiers

PMID: 36161791
DOI: 10.5858/arpa.2021-0601-OA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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