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Article

Association of cup-like nuclei in blasts with FLT3 and NPM1 mutations in acute myeloid leukemia.

Annals of hematology - 1 Apr 2013

Park Borae G, Chi Hyun-Sook, Jang Seongsoo, Park Chan-Jeoung, Kim Dae-Young, Lee Jung-Hee, Lee Je-Hwan, Lee Kyoo-Hyung

Abstract excerpt

The purpose of this study was to investigate the correlation of mutations of the fms-like tyrosine kinase (FLT3) and nucleophosmin (NPM1) genes with the cup-like nuclear morphology of blasts in patients with acute myeloid leukemia (AML). We retrospectively reviewed peripheral blood (PB) and bone marrow (BM) slides of 208 patients prepared at the time of diagnosis of AML based on the results of testing for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23238897
DOI: 10.1007/s00277-012-1645-5

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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