Article
Early Prediction and Streamline of Nucleophosmin Mutation Status in Acute Myeloid Leukemia Using Cup-Like Nuclear Morphology.
Medicina (Kaunas, Lithuania) - 4 Sept 2024
Jakovic Ljubomir, Djordjevic Vesna, Kraguljac Kurtovic Nada, Virijevic Marijana, Mitrovic Mirjana, Trajkovic Lazar, Vidovic Ana, Bogdanovic Andrija
Abstract excerpt
Background and Objectives: With the advent of novel therapies for nucleophosmin gene (NPM1)-mutated acute myeloid leukemia (AML), there is a growing need for the reliable prediction of NPM1 mutations. This study explored the role of cytomorphological features in the early prediction of NPM1-mutated AML. Materials and Methods: Altogether, 212 de novo AML cases with normal karyotypes, diagnosed and treated at a...
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