Article
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome
21 Sept 2022
Abstract excerpt
Many cancers are organized as cellular hierarchies sustained by cancer stem cells (CSC), whose eradication is crucial for achieving long-term remission. Difficulties to isolate and undertake in vitro and in vivo experimental studies of rare CSC under conditions that preserve their original properties currently constitute a bottleneck for identifying molecular mechanisms involving coding and non-coding genomic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.