Article

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics

2018-12-21

Abstract excerpt

Cancer stem cells drive disease progression and relapse in many types of cancer. Despite this, a thorough characterization of these cells remains elusive and with i the ability to eradicate cancer at its source. In acute myeloid leukemia (AML), leukemic stem cells (LSCs) underlie mortality but are difficult to isolate due to their low abundance and high similarity to healthy hematopoietic stem cells (HSCs). Here,...

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Literature Corpus work: cd80e457-917e-5bbd-959b-64f381173e9f
DOI: 10.1101/500108

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