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Article

Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer.

BMC cancer - 31 Aug 2022

Kim Kyoung Min, Ahn Ae-Ri, Park Ho Sung, Jang Kyu Yun, Moon Woo Sung, Kang Myoung Jae, Ha Gi Won, Lee Min Ro, Chung Myoung Ja

Abstract excerpt

In human colorectal cancer (CRC), TP53 is one of the most important driver genes. Immunohistochemistry (IHC) has been used most often to assess the variational status of TP53. Recently, next-generation sequencing (NGS) of the TP53 gene has increased. However, to our knowledge, a comparison between TP53 status evaluated by IHC and NGS has not been studied. Therefore, the primary aim of this study was to compare...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 36045334
DOI: 10.1186/s12885-022-10039-y
PMCID: PMC9434900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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