Article

Studying the Impact of Tp53 Mutations on Colorectal Cancer Pathogenesis and Therapeutic Response in a Tunisian Population

2026-04-15

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction:</bold> Colorectal cancer has been ranked as the second most deadly cancer and the third most diagnosed cancer for the year 2020.TP53 a pivotal tumor suppressor gene, is frequently mutated in colorectal cancer (CRC), influencing tumorigenesis and therapy response. This study investigates the mutational spectrum of TP53 in CRC, elucidates its effects on tumor progre...

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Literature Corpus work: dca7fa85-c865-51a5-b006-b8b3814e1593
DOI: 10.21203/rs.3.rs-9381448/v1

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