Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TP53 mutations in epithelial ovarian cancer

1 Dec 2016

Abstract excerpt

Genomic sequencing analyses of a variety of human cancers have revealed that massive mutations of cancer-relevant genes are the major alterations in cancerous cells, and their mutation frequencies or rates are highly associated with the development, progression, metastasis, and drug resistance of cancers as well as their clinical outcomes and prognosis. One predominant genetic alternation in human epithelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways
Share to Ovarian cancer diagnosis and treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30613473
DOI: 10.21037/tcr.2016.08.40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TP53 mutations in epithelial ovarian cancerPMID 30613473Read ↗

TP53 Mutations in Breast and Ovarian Cancer.Semantic proximity Read ↗

TP53 mutations as potential prognostic markers for specific cancers: Analysis of data from The Cancer Genome Atlas and the International Agency for Research on Cancer TP53 DatabaseSemantic proximity Read ↗

Recent advances in the understanding of TP53 in haematological malignancies.Semantic proximity Read ↗

TP53 and ovarian cancer.Semantic proximity Read ↗

Comprehensive omics studies of p53 mutants in human cancer.Semantic proximity Read ↗

TP53 mutations are common in all subtypes of epithelial ovarian cancer and occur concomitantly with KRAS mutations in the mucinous type.Semantic proximity Read ↗

Mutational Landscape of TP53 Across Cancer TypesSemantic proximity Read ↗

Cellular Mechanism of Gene Mutations and Potential Therapeutic Targets in Ovarian CancerSemantic proximity Read ↗

Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer.Semantic proximity Read ↗

Mutated p53 in HGSC—From a Common Mutation to a Target for TherapySemantic proximity Read ↗

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high-grade serous ovarian carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.