Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation analysis of TP53 missense mutations and p53 protein expression patterns in endometrial carcinoma.

Human pathology - 1 May 2026

Yang Ying, Sun Shu, Xi Yun, Xu Chenyang, Zhu Rui, Yin Wenjuan, Zhan Yanyan, Su Dan

Abstract excerpt

p53 abnormality (p53 abn) subtype is a critical category in endometrial carcinoma (EC) molecular classification, yet clinical diagnosis often relies solely on p53 immunohistochemistry (IHC) staining or TP53 gene sequencing. This study aimed to explore the correlation between TP53 genotype and p53 protein expression in EC with TP53 missense mutations, as well as the clinical and prognostic significance of their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor
Share to Endometrial Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TP53 gene

Share to Immunohistochemistry

Share to Mutation, Missense

Share to Phenotype

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 41581707
DOI: 10.1016/j.humpath.2026.106056

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation analysis of TP53 missense mutations and p53 protein expression patterns in endometrial carcinoma.PMID 41581707Read ↗

Correlative Assessment of p53 Immunostaining Patterns and TP53 Mutation Status by Next-Generation Sequencing in High-Grade Endometrial Carcinomas.Semantic proximity Read ↗

p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial.Semantic proximity Read ↗

Significance of TP53 Mutational Status-Associated Signature in the Progression and Prognosis of Endometrial CarcinomaSemantic proximity Read ↗

Impact of TP53 somatic mutations on prognosis in endometrial cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

Identification of molecular subtypes for endometrial carcinoma using a 46-gene next-generation sequencing panel: a retrospective study on a consecutive cohort.Semantic proximity Read ↗

Subclonal p53 immunostaining in the diagnosis of endometrial carcinoma molecular subtype.Semantic proximity Read ↗

Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options.Semantic proximity Read ↗

TP53 mutations in epithelial ovarian cancerSemantic proximity Read ↗

p53 immunohistochemistry is an accurate surrogate for TP53 mutational analysis in endometrial carcinoma biopsies.Semantic proximity Read ↗

p53 Immunohistochemical Staining and TP53 Gene Mutations in Endometrial Cancer: Does Null Pattern Correlate With Prognosis?Semantic proximity Read ↗

Mutations in cancer-relevant genes are ubiquitous in histologically normal endometrial tissue.Semantic proximity Read ↗

Histopathologic features and molecular genetic landscape of HER2-amplified endometrial carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.