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Article

The heterogeneous impact of targeted therapy on the prognosis of stage III/IV colorectal cancer patients with different subtypes of TP53 mutations.

Cancer medicine - 1 Dec 2023

Chen Jie, Chang Xiaona, Li Xinyi, Liu Jiaying, Wang Na, Wu Ying, Zheng Liduan, Nie Xiu

Abstract excerpt

BACKGROUND: The relationship between molecular characteristics and the prognosis of colorectal cancer (CRC) patients has not been fully understood. This study explored the impact of targeted therapy on the prognosis of CRC patients with different TP53 mutations, in the context of comprehensive treatment. METHODS: This study included patients with stage III/IV primary CRC from the electronic medical record system....

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Identifiers

PMID: 38063316
DOI: 10.1002/cam4.6766
PMCID: PMC10757131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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