Article

Clinical significance of p53 protein expression and TP53 mutation status in colorectal cancer

2022-03-18

Abstract excerpt

In human colorectal cancer (CRC), TP53 is one of the most important driver genes. Immunohistochemistry (IHC) has been used most often to assess the mutational status of TP53 . Recently, next-generation sequencing (NGS) of the TP53 gene has increased. However, to our knowledge, a comparison between TP53 status evaluated by IHC and NGS has not been studied. Therefore, the primary aim of this study was to compare the...

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Literature Corpus work: 642c460c-45bd-56df-a260-26c1aa3a666e
DOI: 10.21203/rs.3.rs-1413512/v1

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