Article
Use of breast surveillance between women with pathogenic variants and variants of uncertain significance in breast cancer susceptibility genes.
Cancer - 1 Oct 2022
Makhnoon Sukh, Chen Minxing, Levin Brooke, Ensinger Megan, Mattie Kristin D, Grana Generosa, Shete Sanjay, Arun Banu K, Peterson Susan K
Abstract excerpt
BACKGROUND: Use of surveillance mammography and magnetic resonance imaging (MRI) has been understudied among women with variant of uncertain significance (VUS) compared to pathogenic and likely pathogenic variants (P/LP). METHODS: Using data from two cancer settings, we calculated use of risk-reducing mastectomy (RRM) and surveillance during each 13-month span after genetic testing up to 6 years afterwards for a...
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