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Utilization of Cancer Screening, Prevention, and Treatment in Women With Variants of Uncertain Significance in Breast Cancer Susceptibility Genes.

Journal of the National Comprehensive Cancer Network : JNCCN - 30 Apr 2025

Nielsen Sarah M, Russell Emily M, Ellsworth Rachel E, Hughes Kevin S, Heald Brandie, Beitsch Peter D, Moretz Chad, Pineda-Alvarez Daniel E, Esplin Edward D, Nussbaum Robert L, Facio Flavia M, Kurian Allison W

Abstract excerpt

BACKGROUND: The presence of variants of uncertain significance (VUS) should not influence clinical management; however, prior studies on breast cancer-related health care utilization in women with VUS versus negative germline genetic test results have shown conflicting findings. This study evaluated whether receipt of a VUS influences breast cancer-related health care utilization. METHODS: This large study...

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PMID: 40306323
DOI: 10.6004/jnccn.2025.7011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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