Risk-Reducing Interventions in Women With Pathogenic Variants in Breast Cancer Susceptibility Genes.

doi:10.1200/PO-26-00373

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Article

Risk-Reducing Interventions in Women With Pathogenic Variants in Breast Cancer Susceptibility Genes.

JCO precision oncology - 1 Aug 2026

Russell Emily M, Nielsen Sarah M, Ellsworth Rachel E, Chwan Ko Heidi, Previs Rebecca A, Pineda-Alvarez Daniel E, Esplin Edward D, Hughes Kevin, Gray Stacy W, Tung Nadine M, Kurian Allison W

Abstract excerpt

PURPOSE: Recommendations for clinical management of women with germline pathogenic variants (PVs) in breast cancer susceptibility genes vary by gene. The goal of this study was to examine the utilization of risk-reducing strategies and treatments in women with germline PVs in breast cancer susceptibility genes. METHODS: This cross-sectional study identified women with a PV in at least one of 13 breast cancer...

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Breast Neoplasms
Cross-Sectional Studies
BRCA1 gene
Genetic Predisposition to Disease
Genetic Testing

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Germ-Line Mutation

Risk Reduction Behavior

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Open in PubMed

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PMID: 42647762
DOI: 10.1200/PO-26-00373

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.