Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association of lipid-lowering drugs with aortic aneurysms: a Mendelian randomization study.

European journal of preventive cardiology - 23 Jul 2024

Gao Xiong, Luo Wei, Qu Liyuan, Yang Miaomiao, Chen Siyu, Lei Li, Yan Shaohua, Liang Hongbin, Zhang Xinlu, Xiao Min, Liao Yulin, Lee Alex Pui-Wai, Zhou Zhongjiang, Chen Jiejian, Zhang Qiuxia, Wang Yuegang, Xiu Jiancheng

Abstract excerpt

AIMS: The lack of effective pharmacotherapies for aortic aneurysms (AA) is a persistent clinical challenge. Lipid metabolism plays an essential role in AA. However, the impact of lipid-lowering drugs on AA remains controversial. The study aimed to investigate the genetic association between lipid-lowering drugs and AA. METHODS AND RESULTS: Our research used publicly available data on genome-wide association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Aneurysm
Share to Cholesterol Ester Transfer Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dyslipidemias

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hydroxymethylglutaryl CoA Reductases

Share to Hypolipidemic Agents

Share to Pharmacogenomic Variants

Share to Proprotein Convertase 9

Source

Identifiers

PMID: 38302118
DOI: 10.1093/eurjpc/zwae044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of lipid-lowering drugs with aortic aneurysms: a Mendelian randomization study.PMID 38302118Read ↗

Genetic insights into therapeutic targets for aortic aneurysms: A Mendelian randomization studySemantic proximity Read ↗

Lipid-lowering and antihypertensive drugs on aortic disease risk: insights from Mendelian randomization analysis and real-world pharmacovigilance data.Semantic proximity Read ↗

Lipid-lowering therapies for aortic stenosis: a drug-target Mendelian randomization study.Semantic proximity Read ↗

The causal association between lipid-lowering strategies and risk of intracranial aneurysms: A drug-target Mendelian randomization study.Semantic proximity Read ↗

Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis.Semantic proximity Read ↗

Mendelian randomization analysis of the causal relationship between serum metabolites and thoracic aortic aneurysm.Semantic proximity Read ↗

Effects of blood lipids and lipid‐modifying drugs on intracranial aneurysmsSemantic proximity Read ↗

SGLT2 inhibition, high-density lipoprotein cholesterol and aortic aneurysm: A drug-target Mendelian randomization study.Semantic proximity Read ↗

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation.Semantic proximity Read ↗

Genetic Association between the Levels of Plasma Lipids and the Risk of Aortic Aneurysm and Aortic Dissection: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Association of lipids and lipid-lowering drugs with peripheral arterial disease: A Mendelian randomization study.Semantic proximity Read ↗

Genetic determinants of lipids and cardiovascular disease outcomes: a wide-angled Mendelian randomization investigationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.