Article
Promising Therapeutic Targets for Intracranial Aneurysms: A Systematic Druggable Genome-Wide Mendelian Randomization.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2026
Maimaiti Aierpati, Pan Lin, Liu Yuxin, Huang Mingrui, Ding Weijie, Yang Wenzhuo, Sun Kaijun, Wang Yongxin, Wang Zengliang
Abstract excerpt
BACKGROUND: Intracranial aneurysm (IA), known as pathological dilation of cerebral arteries, commonly occurring at bifurcating arteries, carries a high risk of severe morbidity and mortality if left untreated. Although the treatment and early diagnosis have significantly improved, the complex pathophysiological process of IA formation presents significant challenges in the development of targeted therapies....
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