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Article

Genetic susceptibility and potential therapeutic targets of unruptured intracranial aneurysms: A genome-wide study based on Mendelian randomization.

Clinical neurology and neurosurgery - 1 Feb 2025

Liu Shuming, Guan Huiyuan, Wang Feng

Abstract excerpt

BACKGROUND: At present, although some studies have offered certain insights into the genetic factors related to unruptured intracranial aneurysms (uIAs), the potential genetic targets associated with uIAs remain largely unknown. Thus, this research adopted Mendelian randomization (MR) analysis to study two genome-wide association studies on uIAs, aiming to determine the reliable genetic susceptibility and...

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Identifiers

PMID: 39847889
DOI: 10.1016/j.clineuro.2025.108749

Genes

ATOX1
CITED2
MTMR3
MYADM
SERINC1
SLC20A1

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