Article
Major implications of single nucleotide polymorphisms in human carboxylesterase 1 on substrate bioavailability.
Biotechnology & genetic engineering reviews - 1 Dec 2024
Yerrakula Goutham, Abraham Shyno, John Shiji, Zeharvi Mehrukh, George Samuel Gideon, Senthil V, Maiz Fathi, Rahman Md Habibur
Abstract excerpt
The number of studies and reviews conducted for the Carboxylesterase gene is limited in comparison with other enzymes. Carboxylesterase (CES) gene or human carboxylesterases (hCES) is a multigene protein belonging to the α/β-hydrolase family. Over the last decade, two major carboxylesterases (CES1 and CES2), located at 16q13-q22.1 on human chromosome 16 have been extensively studied as important mediators in the...
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