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Article

Pharmacogenomic assessment of carboxylesterases 1 and 2.

Genomics - 1 Oct 2004

Marsh Sharon, Xiao Ming, Yu Jinsheng, Ahluwalia Ranjeet, Minton Matthew, Freimuth Robert R, Kwok Pui-Yan, McLeod Howard L

Abstract excerpt

Human carboxylesterases 1 and 2 (CES1 and CES2) catalyze the hydrolysis of many exogenous compounds. Alterations in carboxylesterase sequences could lead to variability in both the inactivation of drugs and the activation of prodrugs. We resequenced CES1 and CES2 in multiple populations (n = 120)...

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Source

Identifiers

PMID: 15475243
DOI: 10.1016/j.ygeno.2004.07.008

Genes

CES2
CES1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15475243-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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