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Article

The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect.

Drug metabolism and drug interactions - 1 Jan 2014

Merali Zahra, Ross Stephanie, Paré Guillaume

Abstract excerpt

Human carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2) are serine esterases responsible for the hydrolysis of ester and amide bonds present in a number of pharmaceutical products. Several common genetic variants of the CES1 and CES2 genes have been shown to influence drug metabolism and cl...

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Source

Identifiers

PMID: 24988246
DOI: 10.1515/dmdi-2014-0009

Genes

CES2
CES1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24988246-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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