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Article

Multiethnic polygenic risk prediction in diverse populations through transfer learning

19 Aug 2022

Abstract excerpt

Polygenic risk scores (PRS) leverage the genetic contribution of an individual's genotype to a complex trait by estimating disease risk. Traditional PRS prediction methods are predominantly for the European population. The accuracy of PRS prediction in non-European populations is diminished due to much smaller sample size of genome-wide association studies (GWAS). In this article, we introduced a novel method to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36061179
DOI: 10.3389/fgene.2022.906965

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