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Article

Leveraging the local genetic structure for trans-ancestry association mapping.

American journal of human genetics - 7 Jul 2022

Xiao Jiashun, Cai Mingxuan, Yu Xinyi, Hu Xianghong, Chen Gang, Wan Xiang, Yang Can

Abstract excerpt

Over the past two decades, genome-wide association studies (GWASs) have successfully advanced our understanding of the genetic basis of complex traits. Despite the fruitful discovery of GWASs, most GWAS samples are collected from European populations, and these GWASs are often criticized for their lack of ancestry diversity. Trans-ancestry association mapping (TRAM) offers an exciting opportunity to fill the gap...

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Identifiers

PMID: 35714612
DOI: 10.1016/j.ajhg.2022.05.013
PMCID: PMC9300880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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