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Article

On cross-ancestry cancer polygenic risk scores.

PLoS genetics - 1 Sept 2021

Fritsche Lars G, Ma Ying, Zhang Daiwei, Salvatore Maxwell, Lee Seunggeun, Zhou Xiang, Mukherjee Bhramar

Abstract excerpt

Polygenic risk scores (PRS) can provide useful information for personalized risk stratification and disease risk assessment, especially when combined with non-genetic risk factors. However, their construction depends on the availability of summary statistics from genome-wide association studies (GWAS) independent from the target sample. For best compatibility, it was reported that GWAS and the target sample...

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Identifiers

PMID: 34529658
DOI: 10.1371/journal.pgen.1009670
PMCID: PMC8445431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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