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Article

Impact of Micropolymorphism Outside the Peptide Binding Groove in the Clinically Relevant Allele HLA-C*14 on T Cell Responses in HIV-1 Infection.

Journal of virology - 25 May 2022

Chikata Takayuki, Paes Wayne, Kuse Nozomi, Partridge Thomas, Gatanaga Hiroyuki, Zhang Yu, Kuroki Kimiko, Maenaka Katsumi, Ternette Nicola, Oka Shinichi, Borrow Persephone, Takiguchi Masafumi

Abstract excerpt

There is increasing evidence for the importance of human leukocyte antigen C (HLA-C)-restricted CD8+ T cells in HIV-1 control, but these responses are relatively poorly investigated. The number of HLA-C-restricted HIV-1 epitopes identified is much smaller than those of HLA-A-restricted or HLA-B-restricted ones. Here, we utilized a mass spectrometry-based approach to identify HIV-1 peptides presented by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35475667
DOI: 10.1128/jvi.00432-22
PMCID: PMC9131871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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