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Article

The C-terminal extension landscape of naturally presented HLA-I ligands

2017-11-02

Abstract excerpt

HLA-I molecules play a central role in antigen presentation. They typically bind 9- to 12-mer peptides and their canonical binding mode involves anchor residues at the second and last positions of their ligands. To investigate potential non-canonical binding modes we collected in-depth and accurate HLA peptidomics datasets covering 54 HLA-I alleles and developed novel algorithms to analyze these data. Our results...

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Identifiers and source

Literature Corpus work
40f166b6-3681-56a9-ab00-b7508d0791cf
DOI
10.1101/213264
Open publication

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The C-terminal extension landscape of naturally presented HLA-I ligandsDOI 10.1101/213264
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