Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2010

John Mina, Heckerman David, James Ian, Park Lawrence P, Carlson Jonathan M, Chopra Abha, Gaudieri Silvana, Nolan David, Haas David W, Riddler Sharon A, Haubrich Richard, Mallal Simon

Abstract excerpt

Currently, 1.1 million individuals in the United States are living with HIV-1 infection. Although this is a relatively small proportion of the global pandemic, the remarkable mix of ancestries in the United States, drawn together over the past two centuries of continuous population migrations, provides an important and unique perspective on adaptive interactions between HIV-1 and human genetic diversity. HIV-1 is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptive Immunity
Share to Amino Acid Motifs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Randomized Controlled Trials as Topic

Share to Receptors, Antigen, T-Cell

Share to Western Australia

Source

Open in PubMed Open full text

Identifiers

PMID: 20231689
DOI: 10.4049/jimmunol.0903745
PMCID: PMC3011274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs.PMID 20231689Read ↗

Advantage of rare HLA supertype in HIV disease progression.Semantic proximity Read ↗

Origins and relatedness of human leukocyte antigen class I allele supertypes.Semantic proximity Read ↗

HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.Semantic proximity Read ↗

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.Semantic proximity Read ↗

HIV-1 diversity versus HLA class I polymorphism.Semantic proximity Read ↗

Immunogenetics of HIV disease.Semantic proximity Read ↗

Human leukocyte antigen class I supertypes and HIV-1 control in African Americans.Semantic proximity Read ↗

Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.Semantic proximity Read ↗

Associations of functional human leucocyte antigen class I groups with HIV viral load in a heterogeneous cohort.Semantic proximity Read ↗

Associations of functional HLA class I groups with HIV viral load in a heterogeneous cohortSemantic proximity Read ↗

Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response.Semantic proximity Read ↗

Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.