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Article

Mesenchymal Stem Cells and their Derived Exosomes Promote Malignant Phenotype of Polyploid Non-Small-Cell Lung Cancer Cells through AMPK Signaling Pathway.

Analytical cellular pathology (Amsterdam) - 1 Jan 2022

Wang Lili, Ouyang Mingyue, Xing Sining, Zhao Song, Liu Shuo, Sun Lingyan, Yu Huiying

Abstract excerpt

Chemotherapy is an important method for the treatment of non-small-cell lung cancer (NSCLC), but it can lead to side effects and polyploid cancer cells. The polyploid cancer cells can live and generate daughter cancer cells via budding. Mesenchymal stem cells (MSCs) are pluripotent stem cells with repair and regeneration functions and can resist tissue damage caused by tumor therapy. This study is aimed at...

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Identifiers

PMID: 35419253
DOI: 10.1155/2022/8708202
PMCID: PMC9001126

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