Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGM2-Mediated Autophagy Contributes to the Radio-Resistance of Non-Small Cell Lung Cancer Stem-like Cells

30 Sept 2024

Abstract excerpt

Objectives: Cancer cells with ‘stemness’ are generally resistant to chemoradiotherapy. This study aims to compare the differences in radiation sensitivity of A549 and CD44+A549 stem-like cells to X-rays and carbon ion radiation (C-ions), and to find a target that can kill cancer stem-like cells (CSCs) of non-small cell lung cancer (NSCLC). Methods: The study used two cell lines (A549 and CD44+A549). The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer Cells and Metastasis
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39457544
DOI: 10.3390/biomedicines12102231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGM2-Mediated Autophagy Contributes to the Radio-Resistance of Non-Small Cell Lung Cancer Stem-like CellsPMID 39457544Read ↗

The Role of Autophagy and lncRNAs in the Maintenance of Cancer Stem CellsSemantic proximity Read ↗

Molecular mechanisms of tumor resistance to radiotherapySemantic proximity Read ↗

E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent mannerSemantic proximity Read ↗

Molecular Insights Into Therapeutic Potential of Autophagy Modulation by Natural Products for Cancer Stem CellsSemantic proximity Read ↗

Cancer stem cells (CSCs): key player of radiotherapy resistance and its clinical significanceSemantic proximity Read ↗

The dual role of autophagy in cancer stem cells: implications for tumor progression and therapy resistanceSemantic proximity Read ↗

Targeting Lung Cancer Stem Cells: Research and Clinical ImpactsSemantic proximity Read ↗

Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.Semantic proximity Read ↗

LTF Induces Radioresistance by Promoting Autophagy and Forms an AMPK/SP2/NEAT1/miR-214-5p Feedback Loop in Lung Squamous Cell CarcinomaSemantic proximity Read ↗

Crosstalk between autophagy and CSCs: molecular mechanisms and translational implicationsSemantic proximity Read ↗

The induction of autophagy by γ‐radiation contributes to the radioresistance of glioma stem cellsSemantic proximity Read ↗

Radio-sensitization of mutated KRAS G12C non-small cell lung cancer with KRAS G12C tyrosine kinase inhibitor and Carbon ions irradiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.