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Article

7SK-enriched exosomes suppress the cancer phenotypes in human lung cancer cells: insights from 2D and microfluidic 3D in vitro models.

Scientific reports - 28 Mar 2026

Aghamiri Shahin, Ajoudanian Mohammad, Farhadi Shohreh, Sharifi Kazem, Ghanbarian Hossein

Abstract excerpt

Lung cancer, being the top cause of global cancer-related mortality, calls for effective treatments. RN7SK (7SK) is a long non-coding RNA (lncRNA) that plays a significant role in the regulation of gene transcription and thereby controls essential cellular activities. Limited evidence supports the anticancer potential of 7SK, and its suppressive effects have not been tested against lung cancer. This study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41904181
DOI: 10.1038/s41598-026-40761-7
PMCID: PMC13039293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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