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Selenium Yeast and Fish Oil Combination Diminishes Cancer Stem Cell Traits and Reverses Cisplatin Resistance in A549 Sphere Cells.

Nutrients - 7 Aug 2022

Lai I-Chun, Liao Chien-Huang, Hu Ming-Hung, Chang Chia-Lun, Lai Gi-Ming, Chiou Tzeon-Jye, Hsia Simon, Tsai Wei-Lun, Lin Yu-Yin, Chuang Shuang-En, Whang-Peng Jacqueline, Chen Hsuan-Yu, Yao Chih-Jung

Abstract excerpt

Cisplatin is a prevalent chemotherapeutic agent used for non-small cell lung cancer (NSCLC) that is difficult to treat by targeted therapy, but the emergence of resistance severely limits its efficacy. Thus, an effective strategy to combat cisplatin resistance is required. This study demonstrated that, at clinically achievable concentrations, the combination of selenium yeast (Se-Y) and fish oil (FO) could...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35956408
DOI: 10.3390/nu14153232
PMCID: PMC9370110

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