Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular mechanism of vimentin nuclear localization associated with the migration and invasion of daughter cells derived from polyploid giant cancer cells

13 Oct 2023

Abstract excerpt

BACKGROUND: Polyploid giant cancer cells (PGCCs), a specific type of cancer stem cells (CSCs), can be induced by hypoxic microenvironments, chemical reagents, radiotherapy, and Chinese herbal medicine. Moreover, PGCCs can produce daughter cells that undergo epithelial-mesenchymal transition, which leads to cancer recurrence and disseminated metastasis. Vimentin, a mesenchymal cell marker, is highly expressed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Nuclear Structure and Function
Share to Skin and Cellular Biology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37833712
DOI: 10.1186/s12967-023-04585-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular mechanism of vimentin nuclear localization associated with the migration and invasion of daughter cells derived from polyploid giant cancer cellsPMID 37833712Read ↗

Contributions of the distinct biophysical phenotype of polyploidal giant cancer cells to cancer progression.Semantic proximity Read ↗

Understanding Polyploid Giant Cancer Cells: From Molecular Mechanisms to Clinical ImplicationsSemantic proximity Read ↗

Formation of Polyploid Giant Cancer Cells Involves in the Prognostic Value of Neoadjuvant Chemoradiation in Locally Advanced Rectal CancerSemantic proximity Read ↗

Polyploid giant cancer cells and tumor budding: translation from basic research to clinical applicationSemantic proximity Read ↗

Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future ProspectsSemantic proximity Read ↗

The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancerSemantic proximity Read ↗

Dormant cancer cells and polyploid giant cancer cells: The roots of cancer recurrence and metastasisSemantic proximity Read ↗

Polyploid Giant Cancer Cells (PGCCs): The Evil Roots of CancerSemantic proximity Read ↗

Polyploid giant cancer cells and cancer progressionSemantic proximity Read ↗

Tumor stroma and differentiated cancer cells can be originated directly from polyploid giant cancer cells induced by paclitaxelSemantic proximity Read ↗

Daughter Cells and Erythroid Cells Budding from PGCCs and Their Clinicopathological Significances in Colorectal CancerSemantic proximity Read ↗

MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.