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Article

Incorporating regulatory interactions into gene-set analyses for GWAS data: A controlled analysis with the MAGMA tool.

PLoS computational biology - 1 Mar 2022

Groenewoud David, Shye Avinoam, Elkon Ran

Abstract excerpt

To date, genome-wide association studies have identified thousands of statistically-significant associations between genetic variants, and phenotypes related to a myriad of traits and diseases. A key goal for human-genetics research is to translate these associations into functional mechanisms. Popular gene-set analysis tools, like MAGMA, map variants to genes they might affect, and then integrate genome-wide...

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Identifiers

PMID: 35316269
DOI: 10.1371/journal.pcbi.1009908
PMCID: PMC8939811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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