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nMAGMA: a network enhanced method for inferring risk genes from GWAS summary statistics and its application to schizophrenia

2020-08-15

Abstract excerpt

<h4>Motivation</h4> Annotating genetic variants from summary statistics of genome-wide association studies (GWAS) is crucial for predicting risk genes of various disorders. The multi-marker analysis of genomic annotation (MAGMA) is one of the most popular tools for this purpose, where MAGMA aggregates signals of single nucleotide polymorphisms (SNPs) to their nearby genes. However, SNPs may also affect genes in a...

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Literature Corpus work: 9c997f9e-d306-52a8-ac39-9550e09456c8
DOI: 10.1101/2020.08.15.250282

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